CD79b iFluor™ 647
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Lymphocytes gated PBMCs stained with CD79b (CB3-1) iFluor 647 (RED); Lymphocytes gated PBMCs are used as FMO control (BLUE).
| Conjugation | iFluor™ 647 |
|---|---|
| Antigen | CD79b |
| Clone | CB3-1 |
| Isotype | IgG1, k |
| Applications | FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Primary/Secondary | Primary |
| Storage | 2-8°C |
| Status | RUO |
Description:
The clone CB3-1, a mouse monoclonal antibody recognizes a 37-39 kD type I integral membrane protein known as CD79. CD79 is a heterodimeric molecule comprised of an alpha-chain (CD79a) and a beta-chain (CD79b). It is noncovalently associated with the CD79a and cell surface IgM to form the B-cell receptor (BCR) complex. CD79b expression is exclusive to B lymphocytes and B cell lymphomas. It can be expressed either in the cytoplasm or on the cell surface depending on the maturation state of the B cells. The CD79 receptor complex triggers numerous signaling pathways to mediate B cell development, maintenance, and activation.
The clone CB3-1, a mouse monoclonal antibody recognizes a 37-39 kD type I integral membrane protein known as CD79. CD79 is a heterodimeric molecule comprised of an alpha-chain (CD79a) and a beta-chain (CD79b). It is noncovalently associated with the CD79a and cell surface IgM to form the B-cell receptor (BCR) complex. CD79b expression is exclusive to B lymphocytes and B cell lymphomas. It can be expressed either in the cytoplasm or on the cell surface depending on the maturation state of the B cells. The CD79 receptor complex triggers numerous signaling pathways to mediate B cell development, maintenance, and activation.
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