TRBC1 FITC
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Lymphocytes gated PBMCs stained with anti-TRBC1 (JOVI.1) FITC (RED); Lymphocytes gated PBMCs are used as FMO control (BLUE).
| Conjugation | FITC |
|---|---|
| Antigen | TRBC1 |
| Clone | JOVI.1 |
| Isotype | IgG2a, k |
| Applications | FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Primary/Secondary | Primary |
| Immunogen | Human HA1.7 TCR beta chain expressed on transgenic mouse cells |
| Format | 0.09% NaN3, 0.2% BSA (w/v), PBS pH 7.2 |
| Storage | 2-8°C |
| Status | RUO |
Description:
The clone JOVI-1, a mouse monoclonal antibody specifically binds to an epitope of T lymphocytes expressing T cell receptor beta constant 1 and known as TRBC1. JOV1.1 antibody recognizes T cells expressing TCR-Cβ1 and one of several different TCRβ V regions as well as several Cβ1 TCR expressing cell lines including Jurkat, CH7C17, and HA1.7 cells. TRBC1 is useful in clinical assessment of T-cell clonality and T-cell neoplasms.
The clone JOVI-1, a mouse monoclonal antibody specifically binds to an epitope of T lymphocytes expressing T cell receptor beta constant 1 and known as TRBC1. JOV1.1 antibody recognizes T cells expressing TCR-Cβ1 and one of several different TCRβ V regions as well as several Cβ1 TCR expressing cell lines including Jurkat, CH7C17, and HA1.7 cells. TRBC1 is useful in clinical assessment of T-cell clonality and T-cell neoplasms.
From Idea to Antibody