TCR α/β PE
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Lymphocytes-gated PBMCs stained with TCR alpha beta (IP26) PE (RED); Lymphocytes gated PBMCs are used as FMO control (BLUE).
| Conjugation | PE |
|---|---|
| Antigen | TCR α/β |
| Clone | IP26 |
| Isotype | IgG1, k |
| Applications | FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Primary/Secondary | Primary |
| Format | 0.09% NaN3, 0.2% BSA (w/v), PBS pH 7.2 |
| Storage | 2-8°C |
| Status | RUO |
Description:
TCRα/β (T-cell receptor) is a 40-55 kD disulfide-linked membrane bound heterodimeric protein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules and binding of the TCRα/β with a peptide bound to MHC leads to T-cell activation. The IP26 antibody reacts with a monomorphic determinant of the α/β T-cell receptor, which is expressed on greater than 95% of normal peripheral blood CD3+ T cells, and it’s a unique mAb triggering T cell activation.
TCRα/β (T-cell receptor) is a 40-55 kD disulfide-linked membrane bound heterodimeric protein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules and binding of the TCRα/β with a peptide bound to MHC leads to T-cell activation. The IP26 antibody reacts with a monomorphic determinant of the α/β T-cell receptor, which is expressed on greater than 95% of normal peripheral blood CD3+ T cells, and it’s a unique mAb triggering T cell activation.
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