Perforin PE
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Lymphocytes gated PMA stimulated fixed and permeabilized PBMCs intracellularly stained with Perforin (B-D48) PE (RED); Lymphocytes gated PMA stimulated fixed and permeabilized PBMCs are used as FMO control (BLUE).
| Conjugation | PE |
|---|---|
| Antigen | Perforin |
| Clone | B-D48 |
| Isotype | IgG1, k |
| Applications | FC |
| Reactivity | Human |
| Host | Mouse |
| Primary/Secondary | Primary |
| Format | 0.09% sodium azide, 0.2% BSA (w/v), PBS pH 7.2 |
| Storage | 2-8°C |
| Status | RUO |
Description:
The clone B-D48, a mouse monoclonal antibody selectively recognizes ~70 KDa cytoplasmic cytotoxic granules pore-forming protein known as Perforin. Perforin is primarily expressed in the cytoplasm of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells through which these cells perform their anti-viral and antitumor killing activities.
The clone B-D48, a mouse monoclonal antibody selectively recognizes ~70 KDa cytoplasmic cytotoxic granules pore-forming protein known as Perforin. Perforin is primarily expressed in the cytoplasm of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells through which these cells perform their anti-viral and antitumor killing activities.
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