Purified E-rosette forming cells from human peripheral blood lymphocytes
CD99 iFluor™ 488
The clone HO36.1.1, a mouse monoclonal antibody selectively binds to a sialoglycoprotein of 27-32 kDa known as CD99 or MIC2 gene product. CD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes and granulosa cells of the ovary, sertoli cells of testis, pancreatic islet cells and some endothelial cells. CD99 is strongly expressed on Ewing's sarcoma cells and primitive peripheral neuroectodermal tumors. It has been reported that CD99 can affect the migration, invasion and metastasis of tumor cells.