Human T lymphocytes
CD45 mFluor™ 450
The CD45 antigen is present on all human leucocytes including lymphocytes, monocytes, granulocytes, eosinophils, and basophils in peripheral blood. The antigen has a role in signal transduction, modifying signals from other surface molecules. The CD45 has been reported to react weakly with mature circulating erythrocytes and plateletsThe recognizes the human leukocyte common antigen which is found on cells from spleen, lymph nodes, 83% bone marrow cells and granulocytes. The antigen recognized by F10-89-4 is a glycoprotein with a molecular weight of 190kDa to 215kDa.