CD43 Unconjugated
Catalog #
Size
Price
| Conjugation | Unconjugated |
|---|---|
| Antigen | CD43 |
| Clone | C-E7A3 |
| Isotype | IgG1, k |
| Applications | FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Primary/Secondary | Primary |
| Storage | 2-8°C |
| Status | RUO |
Description:
The clone C-E7A3, recognizes cell surface protein antigen having molecular weight 115-130 kDa known as CD43 (also known as sialophorin or leukosialin). Sialophorin is a major sialoglycoprotein present on the surface of human T lymphocyte, monocytes, granulocyte, and some of B lymphocytes, which regulates multiple immune function and may be part of a physiological ligand-receptor complex involved in T-cell activation. Therefore, the CD43 expression can be observed at high levels on all leukocytes except for most resting B lymphocytes. In hematopathology, CD43 is often considered as a T-cell associated marker as it is expressed by over 95% of thymocytes and peripheral blood T cells.
The clone C-E7A3, recognizes cell surface protein antigen having molecular weight 115-130 kDa known as CD43 (also known as sialophorin or leukosialin). Sialophorin is a major sialoglycoprotein present on the surface of human T lymphocyte, monocytes, granulocyte, and some of B lymphocytes, which regulates multiple immune function and may be part of a physiological ligand-receptor complex involved in T-cell activation. Therefore, the CD43 expression can be observed at high levels on all leukocytes except for most resting B lymphocytes. In hematopathology, CD43 is often considered as a T-cell associated marker as it is expressed by over 95% of thymocytes and peripheral blood T cells.
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