Conjugation | iFluor™ 488 |
---|---|
Antigen | CD20 |
Size | 25 Tests, 100 Tests, 200 Tests |
Clone | 2H7 |
Isotype | IgG2b, k |
Applications | FC |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Primary/Secondary | Primary |
Storage | 2-8°C |
Status | RUO |
Excitation Laser | Red (633nm) |
CD20 iFluor™ 488
CD20, a 33-36 kDa non-glycosylated type 1 transmembrane protein, is expressed by developing, resting and mature B cells, some follicular dendritic cells, and a small subset of mature T cells. B cell CD20 expression is lost upon differentiation into plasma cells. Functionally, CD20 activation contributes to B cell activation, proliferation, and differentiation.