CD20 iFluor™ 488
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Lymphocytes gated PBMCs stained with CD20 (2H7) iFluor488 (RED); Lymphocytes gated PBMCs are used as FMO control (BLUE).
| Conjugation | iFluor™ 488 |
|---|---|
| Antigen | CD20 |
| Size | 25 Tests, 100 Tests, 200 Tests |
| Clone | 2H7 |
| Isotype | IgG2b, k |
| Applications | FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Primary/Secondary | Primary |
| Storage | 2-8°C |
| Status | RUO |
| Excitation Laser | Red (633nm) |
Description:
CD20, a 33-36 kDa non-glycosylated type 1 transmembrane protein, is expressed by developing, resting and mature B cells, some follicular dendritic cells, and a small subset of mature T cells. B cell CD20 expression is lost upon differentiation into plasma cells. Functionally, CD20 activation contributes to B cell activation, proliferation, and differentiation.
CD20, a 33-36 kDa non-glycosylated type 1 transmembrane protein, is expressed by developing, resting and mature B cells, some follicular dendritic cells, and a small subset of mature T cells. B cell CD20 expression is lost upon differentiation into plasma cells. Functionally, CD20 activation contributes to B cell activation, proliferation, and differentiation.
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