Conjugation | PE-CF594 |
---|---|
Antigen | CD13 |
Clone | APN/1464 |
Isotype | IgG1, k |
Applications | FC |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Primary/Secondary | Primary |
Storage | 2-8°C |
Status | RUO |
Excitation Laser | Green (562nm) |
CD13 PE-CF594
Clone APN/1464 recognizes cell surface CD13 antigen, a 150kDa membrane glycoprotein. The CD13 antigen is highly expressed on myeloid-derived hematopoietic cells including granulocytes, monocytes, mast cells, and GM-progenitor cells. CD13 abundantly expresses on most of the malignant cells of myeloid origin such as AML, CML and on a smaller subset of cancer cells of lymphoid origin. Normal lymphocytes, platelets and erythrocytes do not express CD13. CD13 plays and important role in phagocytosis, in the bactericidal/tumoricidal immune process, and in the metabolism of biologically active peptides. It also serves as a receptor for human coronaviruses (HCV).