CD13 PE-CF594
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Monocytes gated PBMCs stained with CD13 (APN:1464) PE-CF594 (RED); Monocytes gated PBMCs are used as FMO control (BLUE).
| Conjugation | PE-CF594 |
|---|---|
| Antigen | CD13 |
| Clone | APN/1464 |
| Isotype | IgG1, k |
| Applications | FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Primary/Secondary | Primary |
| Storage | 2-8°C |
| Status | RUO |
| Excitation Laser | Green (562nm) |
Description:
Clone APN/1464 recognizes cell surface CD13 antigen, a 150kDa membrane glycoprotein. The CD13 antigen is highly expressed on myeloid-derived hematopoietic cells including granulocytes, monocytes, mast cells, and GM-progenitor cells. CD13 abundantly expresses on most of the malignant cells of myeloid origin such as AML, CML and on a smaller subset of cancer cells of lymphoid origin. Normal lymphocytes, platelets and erythrocytes do not express CD13. CD13 plays and important role in phagocytosis, in the bactericidal/tumoricidal immune process, and in the metabolism of biologically active peptides. It also serves as a receptor for human coronaviruses (HCV).
Clone APN/1464 recognizes cell surface CD13 antigen, a 150kDa membrane glycoprotein. The CD13 antigen is highly expressed on myeloid-derived hematopoietic cells including granulocytes, monocytes, mast cells, and GM-progenitor cells. CD13 abundantly expresses on most of the malignant cells of myeloid origin such as AML, CML and on a smaller subset of cancer cells of lymphoid origin. Normal lymphocytes, platelets and erythrocytes do not express CD13. CD13 plays and important role in phagocytosis, in the bactericidal/tumoricidal immune process, and in the metabolism of biologically active peptides. It also serves as a receptor for human coronaviruses (HCV).
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