New products for PNH clinical research!!!
Paroxysmal nocturnal hemoglobinuria (PNH) is a stem cell disorder caused by a mutation of the gene involved in the synthesis of the GPI (glycosylphosphatidylinositol) anchor of a group of surface proteins on circulating cells. Laboratory findings in PNH include typical findings of hemolytic anemia, loss of GPI-anchored proteins.
Flow cytometry will show reduced levels of GPI-anchored proteins on peripheral blood cells.
ASR-grade FLAER (Fluorescein-labeled Proaerolysin), along with antibodies CD45, CD55, CD59, CD14 and CD15, can be used to detect PNH clones (FLAER-negative cells) within the monocytes and granulocytes lineages in the application of multi-color flow cytometry analysis.
We are happy to provide you with free samples for your internal evaluation!
Great Performance Panel:
FLAER iFluor™488, CD59 PE, CD45 PerCP, CD55 APC
Fig. 1. The common PNH flow panel is established by using Caprico products (FLAER iFluor™488, CD59 PE, CD45 PerCP, CD55 APC) in RBC-lysed fresh blood from healthy donors.
FLAER iFluor™488 & FLAER mFluor™450 both are available right now!
Related products of multi-color flow panels are also available, for further information please check links below:
|CD55||CD14||CD33||CD64||10×RBC Lysis buffer|
*ASR: Analyte Specific Reagent. The analytical and performance characteristics of this ASR product are not established.